My research interest currently focuses on two main areas: at the macro-pharmaceutical level, I’m interesting in developing non-invasive drug delivery systems with a particular emphasis on tailoring carriers through different routes of administration. Fundamental pharmaceutical concepts in drug solubilization and controlled-release drug delivery are of interest. In addition to, the elaboration and appraisal procedures and techniques of micro-sized pharmaceutical carriers. Mathematical optimization and assessment of delivery systems covers various routes of administration viz. oral, transdermal, pulmonary and ocular is considered an area of my speciality. At the nanotechnology level, my core of research is the application of nanotechnology in the field of drug delivery with special interest in anticancer and anti-bacterial drugs and targeting. More precisely, these investigations of polymer-, lipid- and peptide-based nano-carriers allow us to explore their in vivo performance on molecular and animal models.
Jana K Alwattar, Amina T Mneimneh, Kawthar K Abla, Mohammed M Mehanna, Ahmed N Allam Smart Stimuli-Responsive Liposomal Nanohybrid Systems: A Critical Review of Theranostic Behavior in Cancer, Pharmaceutics, 2021; 13(3), 355
Mohammed M Mehanna, Kawthar Khalil Abla, Hoda A. Elmaradny “Tailored Limonene-Based Nanosized Microemulsion: Formulation, Physicochemical Characterization and In-vivo Skin Irritation Assessment” Advanced Pharmaceutical bulletin, 2021; 2021,11(2), 274-285
Mohammed M. Mehanna, Amina Tarek Mneimneh “Formulation and Applications of Lipid-based Nanovehicles: Spotlight on Self-Emulsifying Systems” Advanced Pharmaceutical bulletin, 2021; 11(1): 56-67
Mohammed M. Mehanna, Amina Tarek Mneimneh, Souraya Domiati, Ahmed Allam “Tadalafil-loaded Limonene-based Orodispersible Tablets: Formulation, In-vitro Characterization and In-vivo Appraisal of Gastroprotective Activity” International Journal of Nanomedicine, 2020; 15: 10099–10112
Mohammed M. Mehanna, Rana Sarieddine, Jana K. Alwattar, Racha Chouaib, Hala Gali-Muhtasib “Anticancer activity of thymoquinone cubic phase nanoparticles against human breast cancer: formulation, cytotoxicity and subcellular localization” International Journal of Nanomedicine, 2020;15, 9557-9570
Mohammed M. Mehanna, Amina Tarek Mneimneh and Khaled Abed El Jalil “Levofloxacin-loaded naturally occurring monoterpene-based nanoemulgel: a feasible efficient system to circumvent MRSA ocular infections” Drug Development and Industrial Pharmacy, 2020;46 (11):1787–1799
Jana K.Alwattar, Racha Chouaib, Alia Khalil, Mohammed M. Mehanna ‘A novel multifaceted approach for wound healing: Optimization and in vivo evaluation of spray dried tadalafil loaded pro-nanoliposomal powder’ International Journal of Pharmaceutics 2020;587,119647
Mohammed M. Mehanna, and Amina Tarek Mneimneh ‘Updated but not outdated “Gliadin”: A plant protein in advanced pharmaceutical nanotechnologies’ powder’ International Journal of Pharmaceutics 2020;587, 119672
Mohammed M. Mehanna, Jana K. Alwattar, Roland Habchi. “Electrohydrodynamic atomization, a promising avenue for fast-dissolving drug delivery system: Lessons from tadalafil-loaded composite nanofibers” Journal of Applied Pharmaceutical Science, 2020;10(1):33-45
Mohammed M. Mehanna, Jana Elwattar. “Nanosphere-loaded Tadalafil with Enhanced Oral Bioavailability: Innovative Application of Electrohydrodynamic Technique” International Journal of Current Pharmaceutical Research, 2020;12(1):28-34
- Consulting editor at International Journal of Nanomedicine
- Editorial board Member of
a. Journal of Novel Drug Delivery Technology
b. Insights in Tuberculosis
c. Journal of Bioavailability and Bioequivalence
d. International Journal of Pharmacy and Biotechnology
- Peer reviewer in many highly ranked international journals in pharmaceutics and pharmaceutical technology, among them:
International Journal of Pharmaceutics.
International Journal of Nanomedicine.
Journal of Pharmaceutical Science.
Journal of Molecular Pharmaceutics.
Drug Design, Development and Therapy
Drug Development and Industrial Pharmacy.
Journal AOAC International
- Member of scientific research committee, Beirut Arab University, Lebanon.
- Head of library committee, Faculty of Pharmacy, Beirut Arab University, Lebanon.
- Member of postgraduate studies and scientific research committee, Faculty of Pharmacy, Beirut Arab University, Lebanon.
- Member of strategic planning committee, Faculty of Pharmacy, Beirut Arab University, Lebanon.
- Academic advisor for undergraduate students from different levels, Faculty of Pharmacy, Beirut Arab University, Lebanon.
- Member of the Faculty Quality Assurance Unit, Faculty of Pharmacy, Beirut Arab University, responsible for preparation of Canadian pharmacy program accreditation (CPPA) visit, 2014.