INTRODUCTION: The management of facial trauma is one of the most demanding aspects of oral and maxillofacial surgery. Being the most prominent mobile bone of the facial skeleton, mandible fracture occurs more frequently than any other facial fracture. OBJECTIVES: To compare between the effect of three dimensional (3D) plates and conventional miniplates for internal fixation of anterior mandibular fractures. MATERIALS AND METHODS: This was a controlled and randomized clinical trial. A total of 20 patients; aged between 21-50 years, who had symphyseal or parasymphseal mandibular fracture were randomly selected for this study from the outpatient clinic of Oral and Maxillofacial Surgery Department, Faculty of dentistry, Alexandria University. In this study, open reduction and internal fixation were performed for mandibular symphyseal and parasymphyseal region fractures using one three dimensional (3D) plate in 10 patients as study group and using two miniplates in 10 patients as control group. Clinical and radiographical evaluation were made. Each patient was evaluated: 1- clinically for infection, pain, swelling, malocclusion, wound healing, sensory disturbance, primary stability of the fracture segment, maximum mouth opening and masticatory efficiency using pressure indicating film. 2- Radiological: cone beam computed tomography (CBCT) images were taken to evaluate reduction of the fractured segment, malunion/non-union and bone density within the fracture line. The data collected was subjected to statistical analysis. RESULTS: There was an improvement in wound healing, oedema, occlusion and sensory disturbance in both groups. There was no statistical significant difference between the two groups regarding pain, maximum mouth opening, bite force or bone density. CONCLUSIONS: Three dimensional plate is effective in the treatment of anterior mandibular fractures as well as conventional miniplates. Ease of application and shorter working time are its advantages over conventional miniplates. KEY WORDS: 3D plate, Miniplates, Symphyseal, Parasymphyseal, mandibular fracture.