Purpose: To evaluate the influence of different aging techniques on zirconia-composite microtensile bond strength using different surface treatments over a 5-year follow-up period. Materials and Methods: Zirconia disks received three surface treatments: airborne-particle abrasion with 50-μm aluminum oxide particles, selective infiltration etching (SIE), or fusion sputtering (FS). The specimens were bonded to pre-aged composite disks using a composite cement containing phosphate monomers (Panavia F2.0). Bonded specimens were sectioned into microbars (1 x 1 x 6 mm) using a precision cutting machine, and all microbars re- ceived thermocycling (15,000 cycles between 5°C and 55°C). Initial microtensile bond strength was evaluated, and the test was repeated after storage in the following media for five years (artificial saliva, 20% ethanol, 5% NaOH, 4% acetic acid, and 5% phosphoric acid). The test was repeated every 12 months for 5 years. Scanning electron microscopic images were used to analyze the zirconia-composite interface. A repeated measures ANOVA and Bon- ferroni post-hoc tests were used to analyze the data (n = 20, α = 0.05). Results: Significantly higher microtensile bond strength was observed for SIE compared to fusion sputtering and airborne particle abrasion. Five years of artificial aging resulted in significant reduction of zirconia-composite bond strength for all tested specimens. Zirconia-composite bond strength was more sensitive to storage in sodium hy- droxide and phosphoric acid, while it was least affected when stored under saliva. These changes were related to the mechanism of ultra-structural interaction between surface treatment and adhesive, as deterioration of the hy- brid layer (composite-infiltrated ceramic) was responsible for bond degeneration. Conclusion: Zirconia-composite bond strength was influenced by 5 years of artificial aging. Keywords: yttria-stabilized zirconia ceramic, microtensile bond strength, surface treatment, resin cements, durabil- ity, aging, storage media.